|
- The interplay between tumor and nodal microenvironments for . . .
The formation happens when tumor cells create a supportive microenvironment within lymph nodes, facilitating their sur-vival, growth, spread, and invasion This complex mechanism involves multiple steps and cellular interactions between the pri-mary tumor and tumor microenvironment
- The Regulation of Lymph Node Pre-Metastatic Niche Formation . . .
Later related researches (8, 9) have showed the interplay among the microenvironment of the primary and metastatic organs: in order for tumor cells to engraft (metastatic niche) and flourish in secondary locations, a suitable microenvironment (premetastatic niche) must form
- The evolving tumor microenvironment: From cancer initiation . . .
Understanding the complex interplay between tumor cell-intrinsic, cell-extrinsic, and systemic mediators of disease progression is critical for the rational development of effective anti-cancer treatments
- Pre-metastatic niche: formation, characteristics and . . . - Nature
This review delves into the intricate landscape of the pre-metastatic niche, focusing on the roles of tumor-derived secreted factors, extracellular vesicles, and circulating tumor cells in
- Tumor Metabolism in the Microenvironment of Nodal Metastasis . . .
MCT4 is a tumor-specific marker of oxidative stress, glycolysis and hypoxia in tumor stromal cells We investigated HPV positive and negative tumors with regional metastases to cervical lymph nodes (LN) to study how the metastatic tumor cells interact with their microenvironment
- Premetastatic Niche: A Novel Area for Research in Metastasis . . .
Tumor‐derived exosomes have been found to drain to lymph nodes to modify the microenvironment, thus helping a premetastatic niche formation Recently, studies on melanoma revealed exosomes
|
|
|