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- Cocaine-related Chest Pain • LITFL • CCC Toxicology
“Unopposed alpha effect” does occur in coronary artery when a beta-blocker is administered in a setting of acute cocaine exposure beta-blocker use is best avoided in the acute management of cocaine-induce acute chest pain
- Clinical manifestations, diagnosis, and management of the . . .
Cocaine is among the most commonly used illicit recreational drugs worldwide Because even casual use of cocaine may be associated with acute or chronic cardiovascular toxicity, the large numbers of exposed individuals may present with sequelae related to the cardiovascular system
- Do selective beta blockers need to be avoided in the setting of recent . . .
The American College of Cardiology (ACC) and American Heart Association (AHA) guidelines recommend against the use of beta-blockers in patients with ST-elevation myocardial infarction (STEMI) precipitated by cocaine use due to increased risk of coronary spasm exacerbation
- 11. Stimulant (Cocaine, Amphetamine) Overdose and Intoxication
Non-depolarizing agents (rocuronium, vecuronium) are preferred Cocaine-induced QRS prolongation: rare, due Na+ channel blockade Treat with sodium bicarbonate boluses Supraventricular tachycardia: treat as you would in other etiologies (see cardiology SVT section) Avoid beta-blockers Calcium channel blockers are safe to use (e g , diltiazem)
- Management of Cocaine-Associated Chest Pain and Myocardial Infarction
The goals of the present article are to provide a critical review of the literature on cocaine-associated chest pain and myocardial infarction (MI) and to give guidance for diagnostic and therapeutic interventions
- Cocaine-Associated Chest Pain – Diagnosis and Treatment : Emergency Care BC
Coronary angiography with PCI is preferred over fibrinolytics 4,5 If ST-elevation and or ischemic symptoms persist despite therapy, cardiology should be consulted to help guide these treatment decisions
- MMRF Oct 07 Book_RPI - Clinical Medicine Research
Previous studies have shown that coronary artery spasm occurs with cocaine use, and perhaps platelet activation, both contributing to a process that may culminate in coronary artery occlusion
- CASE REpoRt CoCaine induCed Coronary artery spasm leading to st . . .
Previous studies have shown that cocaine use may cause acute coronary occlusion by inducing coronary vasospasm and activating platelets leading to thrombus formation
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