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- Dupilumab May Improve Nasal Passage Microbiota Composition in CRSwNP
Dupilumab treatment in patients with CRSwNP did not change the composition of gastrointestinal microbiota Immunomodulation with dupilumab may foster healthier nasal passage microbiota composition in patients with diffuse type 2 chronic rhinosinusitis with nasal polyps (CRSwNP), researchers reported in Allergy
- Chronic Rhinosinusitis with Nasal Polyps - PMC
While nasal polyps are observed in a variety of clinical conditions including cystic fibrosis and malignancy, they are more frequently associated with a subset of chronic rhinosinusitis aptly named chronic rhinosinusitis with nasal polyps (CRSwNP) In this condition, nasal polyps are benign and typically develop bilaterally in the sinonasal cavity
- Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) - EUFOREA
About Nasal Polyps Nasal polyps are soft, painless and non-cancerous growths that develop in the sinuses and eventually also in the nose due to an inflammation of the mucosa Chronic sinusitis can exist with or without nasal polyps It is still unclear why some patients develop nasal polyps and others do not How do nasal polyps affect my health? Nasal polyps may not cause any symptoms
- Dupilumab Treatment Is Associated With Clinical . . . - Wiley Online Library
Background Nasal microbiota composition of patients with diffuse type 2 chronic rhinosinusitis with nasal polyps (CRSwNP) is altered compared to healthy individuals Dupilumab, an anti-IL-4Rα-mAb, modulates type 2 inflammation, but the effect on microbiota composition in CRSwNP is unknown The aim of this study was to investigate longitudinal effects of dupilumab on the nasal passage and
- A clinical update on chronic rhinosinusitis and nasal polyposis
This review outlines key drivers in the pathogenesis of CRS with and without nasal polyps, current diagnostic tools clinicians can rely on in clinical practice, and current and future treatment options, while providing a general overview of up-to-date guidelines for CRS diagnosis and management
- Nasal Polyps: Medications That Can Help - WebMD
Which medications treat nasal polyps? Find out what medical options there are for shrinking nasal polyps and easing symptoms
- Biologics Shown Effective in Real-World Setting for Managing Patients . . .
How do the clinical effects and response times of dupilumab, omalizumab, and mepolizumab compare when treating patients with severe, uncontrolled chronic rhinosinusitis with nasal polyps (CRSwNP)?
- Chronic Rhinosinusitis with Nasal Polyps - AllergoLyon
Chronic rhinosinusitis includes a heterogeneous group of conditions with differ-ing pathophysiologies Two main subgroups are described: with and without nasal polyps Chronic rhinosinusitis without nasal polyps may be idiopathic or odon-togenic or may be caused by immunodeficiency, vasculitis, or other autoimmune conditions The majority of cases of chronic rhinosinusitis with nasal polyps
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