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- Acute cellulitis and erysipelas in adults: Treatment - UpToDate
For patients who cannot take any beta-lactam agent, we suggest IV vancomycin (table 3) paired with either levofloxacin (750 mg IV once daily) or aztreonam (2 g IV every eight hours; dosing up to 2 g every six hours may be reasonable for weight >120 kg)
- Cellulitis Treatment Management - Medscape
In mild cases of cellulitis treated on an outpatient basis, dicloxacillin, amoxicillin, and cephalexin are all reasonable choices Clindamycin or a macrolide (clarithromycin or azithromycin)
- Guideline for Outpatient Intravenous Management of Cellulitis
If the patient is admitted, antibiotic therapy should be switched to IV Flucloxacillin 1-2g QDS For patients with Penicillin allergy and or prescribed Teicoplanin in accordance with this guideline, contact Microbiologist for advice on the choice of antibiotic on admission
- Skin and Soft Tissue Infections
Clindamycin 300 mg PO TID *TMP SMX and doxycycline have poor activity against Group A streptococci and should be combined with Amoxicillin or Cephalexin Duration: 7-10 days May step down to oral therapy when patient is improving Diabetics: mixed anaerobic and aerobic flora
- Antibiotic Treatment of Cellulitis and Erysipelas - JAMA Network
Oral clindamycin compared with sequential intravenous and oral flucloxacillin in the treatment of cellulitis in adults: a randomized, double-blind trial Infect Dis Clin Pract 2014;22 (6):330-334 doi: 10 1097 IPC 0000000000000146 Google Scholar
- MANAGEMENT OF CELLULITIS IN ADULTS
Penicillin allergy: Clindamycin 1 2g IV QDS + Gentamicin 7mg kg IV (see gentamicin guideline) Note: Fournier’s Gangrene - piperacillin tazobactam IV 4 5g tds
- Management and Treatment of Cellulitis and Erysipelas for Adults
Those at risk could have a 5 day starter supply of either flucloxacillin 500 mg 6 hourly, amoxicillin 500 mg 8 hourly or clindamycin 300 mg 6 hourly PO to take immediately for any new recurrent attack of cellulitis
- Clindamycin | Johns Hopkins ABX Guide
DRUG INTERACTIONS Erythromycin: in vitro antagonism Clinical significance is unclear Avoid co-administration Kaolin-pectin: decreases clindamycin absorption Loperamide and diphenoxylate atropine: may increase the risk of diarrhea and C difficile -associated colitis Avoid use with clindamycin Nondepolarizing muscle relaxant (pancuronium, tubocurarine): lincosamides may enhance the action
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